Hair loss

Harmful negative effects of the steroids -

Often, of the steroids or the steroids anabolic are employed to regulate the body functions or to treat a handle of serious medical conditions. They are also employed as renforceurs of execution, but it should remember that there is a certain number of negative effects of the steroids on the human body. The users steroids often test the negative effects of the steroids in a form or the autre.

There are many negative effects of the steroids; some of the negative effects of the steroids are that they damage the kidneys and the liver, which can cause harmful effects on the body. Some misleading masculines form centres because of the use of the steroids. Because of the increase in the quantity of testosterone inside the body, steroids can pose the serious problems of acne, which are negative effects connected by skin of the steroids. The negative effects of the steroids are also seen in the teenagers maltreating of the steroids.

According to an outline, steroids are maltreated by people of all the ages. A good number of Scot of college turn to other solutions of replacement to help their aptitude. Several athletes address the certain shape of increasing drugs of execution. The reports/ratios proved that 5% of Scot masculines of college employed steroids and women of 2% employ them.

The survey and the made public opinion poll into which children between the ages from 9 to 13 which covered the two children who have and steroids did not employ, that 47 percent of users of drug pled the steroids indicated make with muscular fabric stronger and larger. 43 percent of them which did not employ steroids said that they also believed made drugs of the larger muscles. Only ones brought back the negative effects of the stéroïdes.

The negative effects of the steroids can cause serious troubles of health. Some negative effects more serious or lasting of the steroids include the first loss (hair loss) of hair, headache, giddiness, oscillations of mood (anger, depression and aggression), the hallucinations, intense feelings of mistrust or terror, troubles of sleep, vomiting and nausea, tremor, on high level of the blood pressure, pain in the joints, yellow fever, ulcer of liver, the urinary problems, shortening of the final size of adult, increased the risk to develop the cardiac disorder, race etc

There a very long list of negative effects of the steroids. The women who employ steroids run the risk of male baldness of model. Several negative effects of the steroids are even worse. Some fall into comas after injection from drugs, some can even die of the injections. The negative effects of the steroids can also raise the risk to develop the cardiovascular disease and often have like consequence the hyperinsulinism and the decreased tolerance of glucose, changes in the fraction of lipoprotein, the greatest triglyceride levels, the greatest concentration of several factors of coagulation, the hypertension and the changes of the myocarde.

Often, of the steroids or the steroids anabolic are employed to regulate the body functions or to treat a handle of serious medical conditions. They are also employed as renforceurs of execution, but it should remember that there is a certain number of negative effects of the steroids on the human body. The users steroids often test the negative effects of the steroids in a form or the autre.

The author has a Web site where you can find volumes of information on steroids, steroids anabolic, and on line. You can check his Web site knowledge supplements above and their effects on our corps.

re that last edit: An Antiandrogen blocks the effects of androgens on the androgen receptors.

Androgens are a class of hormones that act as the male sex hormones by binding to the androgen receptors of the body and effecting their biological effects.

An Antiandrogen by blocking the action of androgens (such as Testosterone and Dihydrotestosterone) will cause a severe form of male menopause, or andropause with significant negative effects on the sexual and reproductive systems of a male, such as a loss/reduction of the ability to get and maintain an erection, decline in sperm production and infertility, as well as reversing the positive effects that testosterone/androgens have on all the other cell and tissues of the body, which includes muscles, bone, brain, nerves, skin, hair, heart, kidneys, bone marrow etc.

To understand the physiologic effects of an Antiandrogen on the body one must first understand the biological effects of Testosterone and androgens on the androgen receptors in the body.

Androgens are any molecular structure that will bind to and activate the androgen receptors. This usually means testosterone and dihydrotestoterone, and their active metabolites, but includes many synthetic steroids.

The androgens are only one of five different kinds of natural steroid hormones, (steroid refers to sterol ring, which is cholesterol, and the five different classes of steroid hormones in mammals are all synthesized from cholesterol. In addition to the androgenic steroids (made mainly in the tesicles and to a lesser degree by the adrenal glands), includes estrogens and the progersterones (made mainly in the ovary and the corticosteroids and mineral corticosteroids (made in the adrenal glands).

Androgen receptors are present in very high concentrations in the tissues that form the external genitalia (penis and associated structures) such as the pelvic muscles and prostate, scrotum and testicles. The rise in testosterone and androgen levels at puberty causes the developement of the secondary sexual characteristics that are part of the changes in a boys body at puberty.

Before birth and during fetal development blocking the androgen receptor of a developing male fetus with an Antiandrogen would prevent the development of the a penis causing the male infant to be born with female external genitalia (that is a vagina without a cervix or uterus, and clitoris. As well the testicles would remain undescended. During fetal development any male fetus who cannot respond at the cellular level to Testosterone, whether it is from taking an anti-androgen like Bicalutamide, or 5-alpha-reductase inhibitors, or is a male who has inherited a defective gene causing a defective androgen receptor or defective 5-alpha reductase enzyme and cannot produce dihydrotestosterone will will not develope a penis. Such males are usually phenotypically identified as a female at birth.

In adult males blocking the androgen receptors by Bicalutamide or other Antiandrogen, and eliminating the effect of Testosterone and the other androgens from binding and stimulating the cellular effects of androgens, Bicalutamide will cause a decline in sperm count, infertility, and a sexual difficulties.

The effects of blocking the androgen receptors and blocking the effects of androgens in the body will have significant effects on the ability of a man to get to get and maintain an erection, resulting usually in profound impotence, and a dramatic reduction in the response to erectile dysfunction medications.

Blocking androgens receptors in the brain will eliminate the inhibition of Testosterone on the release of Luteinizing hormone (LH). Since the body will not detect any Testosterone/androgens and their will be a dramatic rise in Luteinizing hormone secretion resulting in a very significant rise in Testosterone and Estrogen levels.

Since an Ant androgen like Bicalutamide will block the effect of Testosterone on all tissues, there will be no response by the body to the increased androgen levels, but the rising sex hormone production will increase the Estrogen levels in the man to be much higher than they would be in a man who has not been taking Bicalutamide. The Estrogen levels will rise until they are high enough to suppress the release of LH which is causing the Estrogen and Testosterone levels to rise. This rise in Estrogen level stimulated by the blockade of the androgen receptor is why some of the side effects of Bicalutamide is breast tenderness and gynecomastia. As well other feminization effects will occur such as fat accumulation on the hips and thighs.

If Bicalutamide is combined with an LHRH analogue or surgical castration then the elevation of Estrogen levels will be prevented and the risks of excessive estrogen will be reduced. But blocking the rise in Estrogen levels will dramatically increase the bone loss and osteoporosis that will result from the effects of Bicalutamide blocking the actions of androgens in the bone. Since both Testosterone and Estrogens are essential for normal bone metabolism, reducing the positive stimulation of both androgens and estrogens on bone metabolism will definitely increase bone loss and osteoporisis.

Muscle, tendons, joints, bone, and connective tissues will also be affected resulting in a loss of physical strength, reduction in bone density, osteoporosis,etc. The effects of an Antiandrogen blockade of the bodies response to Testosterone will be the the opposite of what happen to a boys body at puberty when Testosterone levels rise and Testosterone start to exert there effect on muscle mass and sexual function. And the effects of taking Bicalutamide will essentially be equivalent to a severe form of male andropause since there will be no effect of Testosterone or any other androgen in the body.

External links

• Estrogens are not antiandrogenic. They are antigonadotropic, but that's not the same.
• Reduced functioning of male sex organs does not have to be caused by antigonadotropic effects (eg. from cyproterone acetate). Antiandrogens without such effects (eg. finasteride) can still cause disfunction.
• Progestagen explains the progestational/progestagenic (same meaning, different word) of cyproterone acetate better than progesterone.

-- Kimiko 21:09 5 Jun 2003 (UTC)

What exactly is the point of insisting that hirsutism is "male pattern" something? I found quite a few definitions that do perfectly well without "male pattern" and only speak of excessive hair. That is probably because there is no particular "male pattern" hair anyway - women have much much shorter and thinner hair, but it does not follow a different "pattern". Women don't even have less hair than men, on the average. The only "male pattern" thing with regard to hair is the opposite phenomenon - male pattern baldness. Since the reasons for hair loss in males are distinctively different from those in women, there is indeed a particular male pattern there. So kindly stop reverting this, it is annoying and false. -- AlexR 00:14, 1 Jul 2004 (UTC)

Consequences on reproduction

Does the use of antiandrogenes make a man sterile? Or does it only reduce his fertrility drastically?

2007-03-15 Lena Synnerholm, Märsta, Sweden. —The preceding unsigned comment was added by 217.208.93.34 (talk • contribs).

• as I understand it, it depends on the drug in question. Long-term use of androgen blockers will certainly cause atrophy of the gonads which may or may not be reversible. I believe that after a number of years, fertility may be permanently impaired. (Just my opinion. Not medical advice, etc) - Alison^☺ 18:15, 15 March 2007 (UTC)